One change : please note that Kent
Higgins has agreed to step in for Dean Yager.
Please fax or Email to pre-register.
Nov. 11-13, 1999
Schepens Eye Research Institute
Boston, MA
web: http://color.eri.harvard.edu/agingretina/
THURSDAY 11 November
9:30 9:50 Cone Photoreceptor Changes in Aging and ARM. Stephen Burns, Ann
E. Elsner, John J. Weiter, Schepens Eye Research Inst . Boston, MA
9:50 10:25 The Role of the Crx Gene in Photoreceptor Development. Connie
Cepko . Harvard University. Boston, MA
10:25 10:45 Are there alterations in gene-expression in the human retina
during "normal" aging?. Steve Bernstein. University of Maryland,.
Baltimore, MD
10:45 11:15 Coffee Break.
11:15 11:35 National Institute of Aging and its Programs. Dr. Judith
Finkelstein. NIA. Bethesda, MD
11:35 12:10 Spatial and temporal expression of proteins involved in outer
segment and synapse formation. Anita Hendrickson. University of Washington.
Seattle, WA
12:10 12:30 Early degeneration in the RCS rat retina promotes the
migration and differentiation of grafted neural stem cells. Michael Young,
Jasodhara Ray,Ü Simon J. O. Whiteley,* Henry Klassen,á and Fred H.
GageÜSchepens Eye Research Inst . Boston, MA, Salk Institute for Biological
Studies, La Jolla, CA, CHOC Research, Children's Hospital of Orange County,
Orange, CA 92868
LUNCH
14:00 14:35 Structural changes in the optic nerve of the aging Rhesus
monkey. Julie H. Sandell and Alan Peters, Boston University School of
Medicine. Boston, MA
14:35 15:10 Changes in retinal and cortical function in aging rhesus
monkeys James N. Ver Hoeve, University of Wisconsin, Madison, WI
15:10 15:30 The effects of aging on changes in foveal temporal contrast
sensitivity during recovery from light adaptation. Dean Yager, Hong Zhan
Ling, SUNY College of Optometry. New York, NY
15:30 16:00 Coffee Break. . .
16:00 16:35 Visual Capacity in Aging. Gary Rubin. The Johns Hopkins
University/Institute of Optics. Baltimore, MD, London, England
16:35 16:55 The effects of aging on the detection of the deformation of
circular D4 contour. Yi-Zhong Wang. Retina Foundation of the Southwest.
Dallas, TX
16:55 17:15 Measuring retinal defects with degraded stimuli. Lei Liu.
Lighthouse International. New York, NY
17:15 17:35 Transient agaptation to peripheral glare in the elderly.
Kent Higgins, Janis M. White & Risa Asami Lighthouse International and New
Jersey Health Care System, Lei Liu
5:35 PM Optional Lab Tours and Light Supper
FRIDAY 12 November
8:30 9:05 OXIDATIVE DAMAGE. Garry Handelman . Tufts University. Boston, MA
9:05 9:25 A mouse model for basal laminar deposits: Role of age and
dietary fat. Scott W. Cousins and Karl Csaky Bascom Palmer Eye Inst. Miami,
Fl, and National Eye Institute, Bethesda MD.
9:25 9:45 Measurement of Monosodium Glutamate and other
Pathophysiologically Important Molecules in the Vitreous Humor by Raman
Spectroscopy. Erik Kruger. New York Eye and Ear Infirmary. New York, NY
9:45 10:05 HMG I(Y) proteins mediate Crx transactivation of the rhodopsin
gene. David K-Y Chau, Donald J. Zack*, Santa J. Ono, Schepens Eye Research
Inst . Boston, MA, The Johns Hopkins University, Baltimore, MD.
10:05 10:35 Coffee Break. . .
10:35 11:10 Control of Apoptosis in Drosophila, Hermann Steller .
Massachusetts Institute of Technology. Boston, MA
11:10 11:30 Subtle changes with aging and AMD, detected with imaging and
functional techniques. Ann E. Elsner Lucio Moraes, Eva Beausencourt,
Andreas Remky, Christian Kunze, Stephen A. Burns, Joseph P. Walker, Glenn
L. Wing, Paul A. Raskauskas, Linda M. Kelley, J.J. Weiter, M.E. Hartnett,
Clement L. Trempe Schepens Eye Research Inst . Boston, MA
11:30 11:50 Regulation of retinal neuron survival and optic nerve
regeneration by BCL-2 family members. Dong Feng Chen. Schepens Eye Research
Inst . Boston, MA
LUNCH
13:30 14:05 Findings of a population-based study of vision of the aged in
Marin County, California. Marilyn Schneck . University of California at
Berkeley and Smith-Kettlewell. Berkeley, CA
14:05 14:25 The change in the eye's optical quality with age. James S.
McLellan, Susana Marcos, Stephen Burns, Schepens Eye Research Inst .
Boston, MA
14:25 14:45 Changes in scotopic sensitivity and dark adaptation during
adulthood. Gregory R. Jackson. University of Alabama. Birmingham, AL
14:45 15:05 Flicker sensitivity and cardiovascular function in healthy
middle-aged people. Alvin Eisner. Oregon Health Sciences University.
Portland, OR
15:05 15:25 Epidemiology of macular pigment and vision changes?. Max
Snodderly. Schepens Eye Research Inst . Boston, MA
15:25 15:55 Coffee Break. . .
15:55 16:30 "Cholesterol deposition in Bruch's membrane and the aorta is
there a connection?" Christine Curcio . University of Alabama. Birmingham, AL
16:30 16:50 Is AMD a vascular disorder?. Ephraim Friedman. Harvard
Medical School/MEEI. Boston, MA
16:50 17:10 Natural history of subfoveal occult choroidal
neovascularization in Age-related macular degeneration: an Indocyanine
study.. Giovanni Staurenghi. University Eye Clinic. San Paolo Hospital..
Milan, Italy
17:10 17:30 Retinal hemodynamics in mild ARMD. Gilbert Feke. Schepens
Retina Associates. Boston, MA
17:30 17:50 Altered expression of tubedown-1, a novel acetyltransferace,
in retinal neovascularization. Robert L. Gendron, HÈlËne Paradis, Lisa C.
Adams and William V. Good Childrens Hospital Med Ctr. Cincinnati, Ohio, and
Smith-Kettlewell Eye Research Institute, San Francisco, California 941151.
17:50 18:10 Cytokine effects on barrier function of the retinal pigment
epithelium. Mary E. Hartnett and Pat D'Amore Schepens Eye Research Inst .
Boston, MA
7:00 PM Conference Banquet at the Harvard Club, Downtown Boston
($50/additional)
SATURDAY 13 November
8:30 9:05 The role of lipofuscin in retinal aging and disease. Michael
Boulton . Dept. of Optometry and Visual Science. Cardiff University
Cardiff, United Kingdom
9:05 9:25 The aging RPE: lipofuscin assayed in vivo. Francois Delori.
Schepens Eye Research Inst Boston, MA
9:25 9:45 A search for Macular Pigment Binding Proteins. Alice Adler.
Schepens Eye Research Inst Boston, MA
9:45 10:05 Macular Pigment and ARM. Richard Bone. Florida International
Univ Miami, FL
10:05 10:25 Fas Ligand/Fas mediates apoptosis and oxidant-induced cell
death in cultured human retinal pigment epithelial cells. Shunai Jiang.
Emory University School of Medicine Atlanta, GA
10:25 10:55 Coffee Break. .
10:55 11:30 Functional assessement of retinal degeneration in rodents: a
premonitory to retinal repair. Peter Coffey . University of Sheffield
Sheffield, United Kingdom
11:30 11:50 Objective Evaluation of Macular function using multifocal
ERG. Michael Marmor. Stanford University School of Medicine Stanford, CA
11:50 12:10 Malignant form of age related macular degeneration (AMD).
Tatsuo Hirose. Schepens Retina Associates Boston, MA