********************************************
Postdoctoral/Graduate Student Positions available in Visual Neuroscience
We have been interested for a number of years in using transgenic animal
models (mice and Xenopus tadpoles) to study the development, function and
pathology of the retina. Currently, the main focus is on understanding the
role of neurotrophins and their receptors in the development of
photoreceptors, with particular emphasis on brain derived neurotrophic
factor (BDNF) and its high affinity receptors TrkB and T1/T2. For this
purpose we are using classical gene knockout (J. Neurosci 19:8919-8930,
1999) and conditional, cell-type specific knockout mice to analyze
photoreceptor development, their connections with postsynaptic targets in
the inner retina and their functional integration into the retinal
circuitry.
Although the mouse is a fantastic genetic model system, it is unsuitable for
photoreceptor analysis at the single cell level. In order to gain access to
single, genetically modifiable retinal cells which can be studied using
single cell physiology and imaging, we are developing a transgenic frog
system to geno- and phenocopy the trkB knockout mouse.
Positions are available immediately at the Medical University of South
Carolina in Charleston. Interested Graduate Students would obtain their
degree through the Department of Physiology and Neuroscience. MUSC is close
to the historic district of Charleston, a mid-size city full of charm,
cultural events and water-related recreational opportunities; and the lab is
part of both the newly established Physiology & Neuroscience Department as
well as the Ophthalmology Department, offering close collaborations with
both basic and clinical scientists.
Candidates should have a strong background and interest in retinal biology
and physiology, and experience in molecular biology is essential.
Interested individuals should send a letter stating their research
interested and experience, a CV and names of three references to
Bärbel Rohrer, Ph.D.
Storm Eye Institute
Medical University of South Carolina
Departments of Ophthalmology and Physiology & Neuroscience
167 Ashley Ave, Rm 707
Charleston, SC 29425
or to rohrer@musc.edu
MUSC is an equal opportunity employer.
********************************************
This archive was generated by hypermail 2b29 : Mon Jan 08 2001 - 11:44:50 PST